MIRIZIR

resful sleep on the one you love <3

resful sleep on the one you love <3

Oh Blink 182, you were such a big part of my adolescence, not sure who I’d be without you guys!

(Source: hearts-all-gone, via princesskoopa)

collabprojekt:

Big K.R.I.T.’s latest banger (well, one of them at least) ‘Money on the Floor’ got the video treatment and the visuals are just what you’d imagine: player’s ball at the strip club, slow-motion gyrating booty, piles of dough on ground. Bonus fun: play “Where’s Waldo?” with rapper cameos in this video - I spotted T.I. and Nelly but I’m sure there are more.

Benjamin

Who doesn’t like a big bouncy booty?!? heheh

(Source: notdisposablepics)


The mechanism of action of cannabis
The active ingredient of cannabis is ∆9-tetrahydrocannabinol (∆9-THC) and it is thought to exert its effect by binding to cannabinoid CB1 receptors on pre-synaptic nerve terminals in the brain. ∆9-THC binding to CB1 receptors activates G-proteins that activate/inhibit a number of signal transduction pathways. The G-proteins directly inhibit N and P/Q-type voltage dependant calcium channels and sodium channels and indirectly inhibit A-type calcium channels via inhibition of adenylate cyclase. ∆9-THC binding and G-protein activation also activates inwardly rectifying potassium channels and the MAP kinase signalling pathway. The cumulative effect of these pathways is the euphoric feelings associated with cannabis use.

Now I finally can understand the mechanism of action of marijuana, thanks pharmacy school&#8230;makes smoking ganja a whole new experience for me :) 

The mechanism of action of cannabis

The active ingredient of cannabis is ∆9-tetrahydrocannabinol (∆9-THC) and it is thought to exert its effect by binding to cannabinoid CB1 receptors on pre-synaptic nerve terminals in the brain. ∆9-THC binding to CB1 receptors activates G-proteins that activate/inhibit a number of signal transduction pathways. The G-proteins directly inhibit N and P/Q-type voltage dependant calcium channels and sodium channels and indirectly inhibit A-type calcium channels via inhibition of adenylate cyclase. ∆9-THC binding and G-protein activation also activates inwardly rectifying potassium channels and the MAP kinase signalling pathway. The cumulative effect of these pathways is the euphoric feelings associated with cannabis use.

Now I finally can understand the mechanism of action of marijuana, thanks pharmacy school…makes smoking ganja a whole new experience for me :) 

incredible actor. incredible face. 100% my favorite &lt;3

incredible actor. incredible face. 100% my favorite <3

Seminar 2

So i started the seminar….annnnd i can totally relate to this cat….yep, I strive for beauty, health, strength, solitude and happiness..x100!

Seminar

I’m starting a health seminar….gonna keep up with it hopefully….lets try and get this thing over with….$800 of brainwashing and hopefully a future of healthy decisions.

i need this.

why?

-health
-weightloss
-get my parents off my back
-future decisions will be altered
-happiness?

it starts Monday..

wish me luck!